Recent findings show that using clascoterone cream 1% twice daily for two weeks improves skin hydration without harming the skin’s barrier. This acne treatment may offer a gentle alternative for patients with sensitive skin.
Clascoterone Cream Shows Positive Results for Skin Moisturization
A recent study revealed that clascoterone cream 1%, used twice a day for two weeks, resulted in increased facial moisturization without damaging the skin barrier. The research indicates that the cream might provide mild hydration benefits for patients with acne.
Study Design and Methodology
The study, conducted at a single center, involved 50 patients with an average age of 31.1 years. Participants were assigned to apply approximately 0.5 g of clascoterone cream 1% to either the right or left side of their face for two weeks. The study aimed to assess both moisturization and skin barrier function during treatment.
Results of the Study
After two weeks of use, the side treated with clascoterone cream showed higher skin hydration levels compared to the untreated side. Corneometry readings indicated a significant difference in hydration (131.3 + 42.9 vs. 113.9 + 36.6, P < .001). However, no difference was observed in transepidermal water loss, suggesting that the cream did not damage the skin barrier.
No Irritation or Dryness Observed
The study also found that clascoterone cream did not cause dryness, redness, or irritation at any point during the trial, suggesting it has a favorable tolerability profile. Dr. Zoe Diana Draelos, a dermatologist involved in the study, highlighted this as a unique feature compared to many other acne treatments, which can cause skin irritation.
Benefits for Sensitive Skin
Clascoterone cream’s gentle formulation makes it a suitable option for patients with sensitive skin. According to Dr. Draelos, the cream can be safely used in conjunction with other acne treatments, like benzoyl peroxide or retinoids, without causing irritation or barrier damage.
Conclusion
Clascoterone cream 1% offers a promising treatment for acne without the typical side effects of dryness or irritation. Its ability to hydrate and support the skin barrier makes it a suitable option for patients seeking a gentler solution for their acne management.
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