A recent study published in ACR Open Rheumatology reveals that individuals diagnosed with psoriasis (PsO) at age 43 or older are more likely to develop psoriatic arthritis (PsA) sooner than younger patients. The study, based on longitudinal real-world data, underscores the need for early identification and intervention among PsO patients at risk for PsA.
Researchers from a psoriatic disease biorepository analyzed clinical and demographic data to identify factors influencing the interval between PsO and PsA diagnoses. They found that older age at PsO onset significantly correlated with a shorter time to PsA development. Patients with PsO onset at approximately 42.6 years had a 62% shorter interval to PsA compared to those diagnosed at around 18.9 years.
Additionally, the study highlighted other risk factors such as higher body mass index (BMI), where patients with a BMI of 34 experienced a shorter PsO to PsA interval compared to those with a BMI of 26, though statistical significance was nearly reached.
The findings underscore the challenges in diagnosing PsA promptly, with delays of up to four years reported in some cases. Factors such as cardiovascular disease, metabolic syndrome components, and family history of PsO were also identified as potential indicators of increased PsA risk.
Despite the study’s insights, limitations were noted, including the retrospective design and lack of detailed PsO subtype data. Researchers emphasize the need for enhanced screening protocols and early referral to rheumatologists to improve outcomes for patients with psoriatic diseases.
“This study underscores the importance of early detection and management of PsA in patients with PsO, particularly among older individuals,” concluded the researchers. The findings suggest implications for clinical practice aimed at optimizing health outcomes in psoriatic disease management.
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