Frank Roesken, MD, PhD, is a leading figure in the aesthetics industry, merging his expertise in wound healing and aesthetic dermatology to guide innovations in science-driven, at-home skincare solutions. As the co-founder of NanoFusion, CEO of THERAPEIA Cosmetics, and Medical Advisor at Skin Moderne, a company known for its pioneering biocompatible skincare solutions, Roesken is at the forefront of advancing personalized dermatological care.
Skin Moderne’s latest launch, the Exosomes Regenerative Complex, introduces a next-generation product that leverages plant-derived exosomes extracted from botanicals such as cabbage and cucumber. These exosomes differ from those traditionally sourced from human or animal cells, offering advantages like enhanced safety, sustainability, and equal potency in skin rejuvenation. Unlike human or animal exosomes, which can carry risks of immunogenic reactions, contamination, and complex regulatory requirements, plant-based exosomes provide a more reliable and eco-friendly alternative for topical skincare.
In an exclusive interview, Roesken explains the key differences between plant-derived and human-derived exosomes, emphasizing how plant-based sources present a safer, more scalable solution with fewer safety concerns. He highlights that plant exosomes come with lower risks of contamination and immunological issues, making them ideal for topical use, while human-derived exosomes raise concerns about ethical sourcing, sterility, and regulatory complexity.
Roesken further elaborates on the benefits of plant-derived exosomes for skin health. These exosomes are packed with bioactive compounds that support various skin functions, including boosting cell proliferation, reducing inflammation, strengthening the skin barrier, balancing the microbiome, enhancing hydration, and promoting communication between skin cells.
The surge in popularity of exosomes in dermatology is undeniable, but Roesken warns that much of the growing buzz is driven by marketing claims that lack clinical validation. While some suppliers make exaggerated promises about the anti-aging benefits of exosomes, credible clinical studies confirm that when sourced and tested properly, exosomes can indeed offer significant skin benefits.
What sets Skin Moderne’s exosomes apart from others in the market is their groundbreaking purification process. Many plant exosome extraction methods suffer from low purity and yield, leading to potential damage to the exosomes and a reduction in their effectiveness. Skin Moderne has overcome these challenges with a patented purification technique called Electrophoretic Oscillation Assisted Tangential Flow Filtration. This method uses an alternating electric field to enhance particle separation without damaging the exosomes, preserving their structure and bioactivity. The process is further optimized through ultrafiltration membranes that ensure higher purity and yield of bioactive nanoparticles.
Roesken emphasizes the rigorous testing procedures behind Skin Moderne’s exosome products. After initial isolation and purification, the exosomes are tested on lab-grown skin to ensure the desired biological effects. The product then undergoes human in vivo trials to confirm that the results hold true in real-world applications. This commitment to data-backed efficacy ensures that only the highest-quality ingredients make it to market.
With these advancements, Skin Moderne’s plant-derived exosomes represent a new era in skincare, promising to revolutionize regenerative beauty treatments with a focus on safety, efficacy, and sustainability.
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